Chronic Inflammatory Demyelinating Polyradiculoneuropathy/Nodopathy Interpretation

Available through our international laboratory collaboration with Mayo Clinic Laboratories

Overview

The CIDP / Nodopathy Evaluation, Serum is a specialized autoantibody panel designed to detect immune-mediated neuropathies, particularly:

• Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
• Autoimmune nodopathies

This test is often included in advanced functional medicine tests, integrated medicine testing, and root cause testing programs at a certified functional health centre or longevity lab in Delhi / India.

Functional medicine practitioners in Delhi/India may recommend this test alongside holistic health tests, preventive longevity tests, or biological age test programs to provide comprehensive immune and neurological assessments.

By identifying specific antibodies associated with these peripheral nerve disorders, this test aids in:

• Accurate diagnosis
• Subclassification
• Guiding targeted immunotherapy

Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Test Clinical Utility

This test is useful for:

• Differentiating CIDP from other acquired demyelinating neuropathies
• Identifying autoimmune nodopathies, which may require different treatment strategies
• Supporting treatment selection for immune-mediated neuropathies
• Monitoring patients for disease recurrence or progression

Integration of CIDP antibody testing with functional medicine diagnostics, functional medicine tests, and integrated medicine testing allows a functional health centre or longevity lab in Delhi / India to provide precision care that complements longevity tests and biological age test programs.

Antibodies Evaluated

(May include, depending on clinical indication):

• Contactin-1 (CNTN1) antibodies
• Neurofascin-155 (NF155) antibodies
• Neurofascin-186 (NF186) antibodies
• Contactin-associated protein 1 (CASPR1) antibodies

These antibodies target proteins involved in nerve conduction and myelin integrity and are critical for diagnosing autoimmune paranodal/nodal neuropathies.

Such testing is commonly part of holistic health tests and root cause testing conducted by experienced functional medicine practitioners in Delhi/India.

Specimen Requirements

• Specimen Type: Serum
• Collection: 1 mL serum in a red-top or serum separator tube (SST)
• Stability: Refrigerated; follow provided specimen handling guidelines

Specimen collection protocols are standardized in functional health centres and longevity labs in Delhi / India performing functional medicine diagnostics and functional medicine tests.

CIDP Test Clinical Background

CIDP is a chronic, immune-mediated neuropathy characterized by progressive or relapsing motor and sensory dysfunction due to demyelination of peripheral nerves.

Autoimmune nodopathies are a subset where the immune system targets nodal/paranodal proteins rather than myelin directly.

Correct subclassification is important, as patients with nodopathies may respond differently to standard CIDP treatments, and targeted immunotherapy may be more effective.

This clinical approach aligns with functional medicine tests, integrated medicine testing, and holistic health tests, complementing preventive longevity tests and biological age test assessments.

Turnaround Time

• Estimated: 15–20 days from specimen receipt at the reference laboratory

Advantages of the CIDP Test

• Provides precise antibody identification for accurate diagnosis
• Helps guide personalized immunotherapy strategies
• Performed by a world-leading neuromuscular diagnostics team
• Complements functional medicine diagnostics, root cause testing, and functional medicine tests offered at functional health centres and longevity labs in Delhi / India