Metabolomix+® : Comprehensive, Non-Invasive Functional Nutritional Assessment

Advanced nutritional profiling from first-morning urine, with optional bloodspot and buccal swab add-ons, offered as part of advanced longevity tests, functional medicine tests, and holistic health tests at a specialized functional health centre and longevity lab in delhi / india.

Metabolomix+® is an all-inclusive nutritional assessment used in functional medicine diagnostics and integrated medicine testing to evaluate biochemical markers involved in metabolism, detoxification, mitochondrial function, gut health, amino acid status, and oxidative balance. This comprehensive approach supports root cause testing strategies commonly employed by a functional medicine practitioner in Delhi/India.

Using a simple first-morning void (FMV) urine sample , with the option to add finger-stick bloodspot and buccal swab genetics , this test provides an in-depth picture of a patient’s functional nutrient needs and may complement biological age test insights related to metabolic efficiency and cellular health.

It is one of the most patient-friendly functional medicine tests for determining whether the body requires additional antioxidants, B-vitamins, minerals, digestive support, amino acids, or essential fatty acids. Insights from Metabolomix+® support functional medicine diagnostics by helping clinicians create personalized nutritional interventions aimed at correcting underlying deficiencies, restoring optimal biochemical balance, and supporting long-term wellbeing as part of comprehensive longevity tests.

Who May Benefit From Functional Nutritional Testing?

Metabolomix+® is recommended for patients with chronic symptoms or conditions often evaluated through holistic health tests, integrated medicine testing, and root cause testing, particularly when functional nutrient insufficiencies are suspected.

Common clinical indications include:

• Mood and mental health concerns
• Mitochondrial dysfunction and low energy
• Persistent fatigue
• Chronic stress response
• Systemic inflammation

Abnormal levels of organic acids, amino acids, and fatty acids identified through functional medicine tests and functional medicine diagnostics are associated with multiple conditions such as:

• Depression and anxiety
• Cardiovascular disease
• Cognitive decline
• Diabetes
• Cancer
• Eating disorders (including anorexia)
• Metabolic dysfunction

Note: Testing is not performed for children under 2 years, but the profile includes pediatric reference ranges for ages 2+.

About the Metabolomix+® Profile

Results are organized into functional metabolic categories, allowing clinicians at a functional health centre or longevity lab in delhi / india to rapidly identify areas of imbalance and nutrient demand during integrated medicine testing.

Report Features

• Personalized Results Summary with a visual overview of nutrient needs
• Functional Imbalance Scores highlighting stress in key pathways such as:
• Methylation
• Toxic exposure & detoxification
• Mitochondrial function
• Fatty acid metabolism
• Oxidative stress
• Nutrient Need Summary with clear recommendations for:
• Antioxidants
• B-vitamins
• Minerals
• Essential fatty acids
• GI support
• Amino acids

Interpretation-At-A-Glance Pages

• Educational summaries for patients
• Causes and complications of deficiencies
• Functional roles of each nutrient
• Food sources for dietary support

Metabolomix+® Profile Components

1. Organic Acids (Urine)

Evaluates metabolic pathways, gut microbiome activity, and energy production as part of functional medicine diagnostics and longevity tests.
Includes markers for:

• Malabsorption & dysbiosis (microbial metabolites)
• Mitochondrial energy production (citric acid cycle intermediates)
• Neurotransmitter metabolites (serotonin, dopamine, norepinephrine byproducts)
• Vitamin cofactors (functional B-vitamin assessment)
• Detoxification capacity
• Oxalate metabolism & kidney stone risk

2. Amino Acids (Urine)

Assesses overall protein metabolism and amino acid sufficiency through functional medicine tests and holistic health tests.
Includes:

• Essential amino acids (diet-dependent)
• Nonessential amino acids (endogenous production)
• Intermediary metabolites
• B-vitamin-dependent reactions
• Urea cycle & nitrogen detoxification markers
• Glycine/serine-related metabolites
• Markers of incomplete protein digestion

3. Oxidative Stress (Urine)

Measures markers such as lipid peroxides and 8-OHdG, indicating oxidative damage to lipids and DNA, commonly evaluated during integrated medicine testing and root cause testing.

Add-On Metabolomix+® Components

Essential & Metabolic Fatty Acids (Bloodspot)

Analyzes patterns of:

• Omega-3, Omega-6, Omega-9 fatty acids
• Saturated fatty acids
• Monounsaturated & trans fats
• Delta-6 desaturase activity
• Cardiovascular risk ratios & Omega-3 Index

Comprehensive Urine Element Profile (Urine)

Evaluates 18 toxic elements and 14 nutrient minerals, supporting functional medicine diagnostics and longevity tests related to environmental and nutritional exposures.

Genetic Add-Ons (Buccal Swab)

Screens for key SNPs affecting metabolism and detoxification, commonly reviewed by a functional medicine practitioner in Delhi/India:

• MTHFR
• COMT
• TNF-α
• APOE

What Is Functional Nutritional Assessment?

Functional nutritional testing evaluates how the body’s biochemical pathways are functioning in real time and is a foundational component of functional medicine tests, holistic health tests, and integrated medicine testing.

When organic acids accumulate in urine, it may indicate metabolic blocks caused by:

• Nutrient deficiency
• Enzyme dysfunction
• Genetic variations
• Toxic burden
• Medication effects

Many enzymes require vitamins and minerals as cofactors, and elevated organic acids can reveal nutrient insufficiencies even when blood levels appear normal. Metabolomix+® uses a proprietary, research-based algorithm to generate targeted nutrient recommendations based on these metabolic patterns.

This approach is well established in pediatric and metabolic medicine and is now widely used in adult functional medicine diagnostics to optimize biochemical performance, support biological age test outcomes, and promote long-term health through evidence-based longevity tests.